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E-AB-10051

CASP2 Polyclonal Antibody

Size

£106.20

Was £118.00

SKU:
E-AB-10051
Additional Names:
CASP 2,CASP-2,CASP2,Casp2,Caspase 2,Caspase 2 apoptosis related cysteine peptidase,Caspase-2 subunit p12,Caspase2,ICH 1,ICH 1 protease,ICH 1L,ICH1,ICH1 protease,ICH1L,NEDD-2,NEDD2,Neural precursor cell expressed developmentally down-regulated protein 2,PP
Application:
WB
Concentration:
0.4 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant protein of human CASP2
Uniprot:
P42575
Synonyms:
CASP-2;caspase 2 apoptosis-related cysteine peptidase;caspase-2;ICH1;NEDD-2;NEDD2;neural precursor cell expressed developmentally down-regulated protein 2;PPP1R57;protease ICH-1;protein phosphatase 1, regulatory subunit 57
Extra Details:
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Shipping Conditions:
Blue Ice