D-AB-10441L
SFTPD/SP-D Polyclonal Antibody
Size
£120.60
Was £134.00
- SKU:
- D-AB-10441L
- Additional Names:
- Lung surfactant protein D,PSP-D,Pulmonary surfactant-associated protein D,SP-D,Sftp4,Sftpd
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Mouse, Rat
- Buffer:
- PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
- Immunogen:
- Recombinant Mouse SFTPD/SP-D protein expressed by Mammalian
- Uniprot:
- P50404
- Synonyms:
- AI573415;lung surfactant protein D;PSP-D;pulmonary surfactant-associated protein D;Sf;Sfpd;Sft;Sftp4;SP;SP-D
- Extra Details:
- Pulmonary surfactant-associated protein D (SP-D) is a 43 kDa member of the collectin family of innate immune modulators. Mouse SP-D cDNA encodes a 19 aa signal sequence and a 355 aa mature region with a 25 aa N-terminal linking-region,a 177 aa hydroxyproline and hydroxylysine collagen-like domain,a 46 aa coiled-coil segment,and a 106 aa,C-terminal collectin-like C-type lectin domain . SP-D is found in serum,plasma,broncho-alveolar lavage (BAL) fluid,and amniotic fluid. It also binds SIRP alpha and the calreticulin/CD91 complex on macrophages. SP-D contributes to the lung',s defense against inhaled microorganisms,organic antigens and toxins. It Interacts with compounds such as bacterial lipopolysaccharides,oligosaccharides and fatty acids and modulates leukocyte action in immune response. It may participate in the extracellular reorganization or turnover of pulmonary surfactant. It binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties.
- Shipping Conditions:
- Blue Ice