D-AB-10387L
C3 Polyclonal Antibody
Size
£120.60
Was £134.00
- SKU:
- D-AB-10387L
- Additional Names:
- C3,Complement C3,HSE-MSF,C3a
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Mouse
- Buffer:
- PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
- Immunogen:
- Recombinant Mouse C3 Protein expressed by E.coli
- Uniprot:
- P01027
- Synonyms:
- acylation stimulating protein;AI255234;ASP;complement C3;complement component 3d;complement factor 3;HSE-MSF;Plp
- Extra Details:
- C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently,via its reactive thioester,to cell surface carbohydrates or immune aggregates. Derived from proteolytic degradation of complement C3,C3a anaphylatoxin is a mediator of local inflammatory process. In chronic inflammation,acts as a chemoattractant for neutrophils.It induces the contraction of smooth muscle,increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes. The short isoform has B-cell stimulatory activity.
- Shipping Conditions:
- Blue Ice