D-AB-10385L
GDF-8 Polyclonal Antibody
Size
£120.60
Was £134.00
- SKU:
- D-AB-10385L
- Additional Names:
- GDF-8,GDF8,Growth/differentiation factor 8,MSTN,Myostatin
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
- Immunogen:
- Recombinant Human GDF-8 Protein expressed by E.coli
- Uniprot:
- O14793
- Synonyms:
- GDF8;growth/differentiation factor 8;MSLHP;Myostatin
- Extra Details:
- Growth/differentiation factor 8(Mstn,GDF-8) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. It is expressed specifically in developing and adult skeletal muscle. It exists as a homodimer,and interacts with WFIKKN2,leading to inhibit its activity. This protein can act specifically as a negative regulator of skeletal muscle growth. It regulates cell growth and differentiation in both embryonic and adult tissues.
- Shipping Conditions:
- Blue Ice