D-AB-10380L
SEMA4D Polyclonal Antibody
Size
£120.60
Was £134.00
- SKU:
- D-AB-10380L
- Additional Names:
- A8,BB18,CD100,CD100 antigen,COLL4,Coll 4,Collapsin 4,Collapsin4,GR3,MSEMA,SEM4D,SEMA J,SEMAJ,Sema 4d,SemaH,Semacl2
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
- Immunogen:
- Recombinant Human SEMA4D protein expressed by Mammalian
- Uniprot:
- Q92854
- Synonyms:
- A8;BB18;C9orf164;CD100;coll-4;COLL4;GR3;M-sema-G;sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D;sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, 4D;SEMAJ;semaphorin-4D
- Extra Details:
- Cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. Promotes reorganization of the actin cytoskeleton and plays a role in axonal growth cone guidance in the developing central nervous system. Regulates dendrite and axon branching and morphogenesis. Promotes the migration of cerebellar granule cells and of endothelial cells. Plays a role in the immune system,induces B-cells to aggregate and improves their viability (in vitro). Promotes signaling via SRC and PTK2B/PYK2,which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade. Interaction with PLXNB1 mediates activation of RHOA.
- Shipping Conditions:
- Blue Ice