D-AB-10379L
SEPP1 Polyclonal Antibody

Size
£120.60
Was £134.00
- SKU:
- D-AB-10379L
- Additional Names:
- SELENOP,SELP,SEPP1,SeP,Selenoprotein P
- Application:
- WB, IF
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Rat
- Buffer:
- PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
- Immunogen:
- Recombinant Human SEPP1 protein expressed by E.coli
- Uniprot:
- P49908
- Synonyms:
- selenoprotein P;selenoprotein P, plasma, 1;SELP;SeP;SEPP;SEPP1
- Extra Details:
- Selenoprotein P (SeP) is an extracellular,monomeric glycoprotein containing up to 10 selenocysteine residues in the polypeptide chain. It is ubiquitously expressed in mammalian tissues,and in human plasma it accounts for at least 40% of the total selenium concentration. SeP binds to heparin and cell membranes,and is associated with endothelial cells. SeP in human plasma protects against peroxynitrite-mediated oxidation and reduces phospholipid hydroperoxide in vitro,in accordance with the presumption that it has a function as an extracellular oxidant defense. Immunochemical assays have demonstrated that its concentration in plasma varies much with selenium intake,but other factors also have an influence.
- Shipping Conditions:
- Blue Ice