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D-AB-10370L

CD74 Polyclonal Antibody

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£120.60

Was £134.00

SKU:
D-AB-10370L
Additional Names:
CD 74,CD74,CD74 antigen,CD74 antigen (invariant polypeptide of major histocompatibility complex,CD74 molecule,CLIP,DHLAG,Gamma chain of class II antigens,class II antigen-associated),class II invariant chain,major histocompatibility complex
Application:
IHC
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human
Buffer:
PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
Immunogen:
Recombinant Mouse Cd74 protein expressed by E.coli
Uniprot:
P04441
Synonyms:
C;class II-associated invariant chain peptide;CLIP;DHLAG;dinucleotide microsatellite;H-2 class II histocompatibility antigen gamma chain;histocompatibility: class II antigens, gamma chain of;HLA-DR-GAMMA;HLADG;ia antigen-associated invariant chain;Ia-associated invariant chain;Ia-GAMMA;Ii;ii chain;invariant polypeptide of major histocompatibility complex, class II antigen-associated;MHC class II-associated invariant chain
Extra Details:
The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Shipping Conditions:
Blue Ice