D-AB-10224L
PCK1 Polyclonal Antibody
Size
£120.60
Was £134.00
- SKU:
- D-AB-10224L
- Additional Names:
- GTP,PCK1,PCKGC,PEP carboxykinase,PEPCK-C,PEPCK1,PEPCKC,Phosphoenolpyruvat,Phosphoenolpyruvate carboxykinase,Phosphoenolpyruvate carboxykinase 1,Phosphoenolpyruvate carboxykinase 1 (soluble),cytosolic [GTP]
- Application:
- IHC
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Rat
- Buffer:
- PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
- Immunogen:
- Recombinant Rat PCK1 protein expressed by E.coli
- Uniprot:
- P07379
- Synonyms:
- GTP;PCK;Pepck;PEPCK-C;phosphoenolpyruvate carboxykinase (GTP);phosphoenolpyruvate carboxykinase 1 (soluble);phosphoenolpyruvate carboxykinase 1, cytosolic;phosphoenolpyruvate carboxykinase, cytosolic (GTP);phosphoenolpyruvate carboxykinase, cytosolic [GTP];phosphoenolpyruvate carboxylase;RATPEPCK;serine-protein kinase PCK1
- Extra Details:
- This gene is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene,along with GTP,catalyzes the formation of phosphoenolpyruvate from oxaloacetate,with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin,glucocorticoids,glucagon,cAMP,and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of the encoded protein also has been characterized.
- Shipping Conditions:
- Blue Ice