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D-AB-10210L

LDHA Polyclonal Antibody

Size

£120.60

Was £134.00

SKU:
D-AB-10210L
Additional Names:
GSD11, L lactate dehydrogenase A chain, LDH M, LDH muscle subunit, LDH1, PIG19 Proliferation-inducing gene 19, l7R2,Cell proliferation-inducing gene 19 protein
Application:
IHC, WB
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
Immunogen:
Recombinant Human LDHA protein expressed by E.coli
Uniprot:
P00338
Synonyms:
cell proliferation-inducing gene 19 protein;epididymis secretory sperm binding protein Li 133P;GSD11;HEL-S-133P;L-lactate dehydrogenase A chain;lactate dehydrogenase M;LDH muscle subunit;LDH-A;LDH-M;LDHM;PIG19;proliferation-inducing gene 19;renal carcinoma antigen NY-REN-59
Extra Details:
LDHA,also named as LDH-M and NY-REN-59,is an enzyme which catalyzes the inter-conversion of pyruvate and L-lactate with concomitant inter-conversion of NADH and NAD+. LDHA is found in most somatic tissues,though predominantly in muscle tissue and tumours,and belongs to the lactate dehydrogenase family. It has long been known that many human cancers have higher LDHA levels compared to normal tissues. It has also been shown that LDHA plays an important role in the development,invasion and metastasis of malignancies. Mutations in LDHA have been linked to exertional myoglobinuria. LDHA has some isoforms with MW 26-40 kDa.
Shipping Conditions:
Blue Ice