D-AB-10207L
JNK2 Polyclonal Antibody
Size
£120.60
Was £134.00
- SKU:
- D-AB-10207L
- Additional Names:
- MAPK,PRKM,JNK,MAPK9,JNK-55,JNK2,JNK2A,JNK2ALPHA,JNK2B,JNK2BETA,PRKM9,SAPK,SAPK1a,p54a,p54aSAPK,c Jun kinase 2,C Jun N terminal kinase 2,c-Jun N-terminal kinase 2,JNK 55,JNK2 alpha,JNK2 beta,Jun kinase,MAP kinase 9,MAPK 9,Mitogen activated protein kinase 9,mitogen-activated,Mitogen-activated protein kinase 9,MK09,Protein kinase,SAPK alpha,Stress activated protein kinase 1a,Stress-activated protein kinase JNK2
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
- Immunogen:
- Recombinant Human MAPK9 protein expressed by E.coli
- Uniprot:
- P45984
- Synonyms:
- c-Jun kinase 2;c-Jun N-terminal kinase 2;JNK-55;JNK2;JNK2A;JNK2ALPHA;JNK2B;JNK2BETA;Jun kinase;MAP kinase 9;MAPK 9;mitogen-activated protein kinase 9;p54a;p54aSAPK;PRKM9;SAPK;SAPK1a;stress-activated protein kinase 1a;stress-activated protein kinase JNK2
- Extra Details:
- The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase targets specific transcription factors, and thus mediates immediate-early gene expression in response to various cell stimuli. It is most closely related to MAPK8, both of which are involved in UV radiation induced apoptosis, thought to be related to the cytochrome c-mediated cell death pathway. This gene and MAPK8 are also known as c-Jun N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor p53, and thus it increases the stability of p53 in nonstressed cells. Studies of this gene's mouse counterpart suggest a key role in T-cell differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported.
- Shipping Conditions:
- Blue Ice