D-AB-10195L
TIMP1 Polyclonal Antibody
Size
£120.60
Was £134.00
- SKU:
- D-AB-10195L
- Additional Names:
- Clgi,Collagenase inhibitor,EPA,EPO,Erythroid Potentiating Activity,Erythroid-potentiating activity,FLJ90373,Fibroblast collagenase inhibitor,HCI,Human,Human Collagenase Inhibitor,Metalloproteinase inhibi,Metalloproteinase inhibitor 1
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Mouse
- Buffer:
- PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
- Immunogen:
- Recombinant Mouse Timp1 protein expressed by E.coli
- Uniprot:
- P12032
- Synonyms:
- Cl;Clgi;collagenase inhibitor 16C8 fibroblast;EPA;erythroid-potentiating activity;metalloproteinase inhibitor 1;Timp;TIMP-1;tissue inhibitor of metalloproteinases 1;TPA-induced protein;TPA-S1
- Extra Details:
- This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction.
- Shipping Conditions:
- Blue Ice