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D-AB-10181L

LUM Polyclonal Antibody

Size

£120.60

Was £134.00

SKU:
D-AB-10181L
Additional Names:
KSPG lumican,Keratan sulfate proteoglycan lumican,LDC,LUM,Lumican,Lumican precursor,SLRR2D
Application:
WB
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
Immunogen:
Recombinant Human LUM protein expressed by E.coli
Uniprot:
P51884
Synonyms:
epididymis secretory sperm binding protein;keratan sulfate proteoglycan lumican;KSPG lumican;LDC;lumican;lumican proteoglycan;SLRR2D
Extra Details:
Lumican (LUM), a member of the small leucine-rich proteoglycan (SLRP) family, is one of the major extracellular components in interstitial collagenous matrices of the corneal stroma, aorta, skin, skeletal muscle, lung, kidney, bone, cartilage, and intervertebral discs. SLRPs constitute an important fraction of noncollagenous extracellular matrix proteins and have important effects on cell behavior. Lumican regulates collagenous matrix assembly as a keratan sulfate proteoglycan in the cornea and may exist as a glycoprotein in the connective tissues of other organs. Posttranslational modifications lumican goes through can increase its apparent molecular weight to 50-90 kDa. Studies show that lumican participates in the maintenance of tissue homeostasis and modulates cellular functions including cell proliferation, migration, and differentiation.
Shipping Conditions:
Blue Ice