AN302084L
Recombinant Phospho-FADD (S194) Monoclonal Antibody
Size
£252.90
Was £281.00
- SKU:
- AN302084L
- Additional Names:
- GIG,MORT,FADD,GIG3,MORT1,Fas associated via death domain,FADD protein,Fas (TNFRSF6) associated via death domain,Fas associating death domain containing protein,Fas associating protein,Fas associating protein with death domain,Fas TNFRSF6 associated via death domain,FAS-associated death domain protein,FAS-associating death domain-containing protein,GIG 3,Growth inhibiting gene 3 protein,Growth-inhibiting gene 3 protein,H sapiens mRNA for mediator of receptor induced toxicity,Mediator of
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant human FADD (phospho S194) fragment
- Clone:
- A808
- Uniprot:
- Q13158
- Synonyms:
- Fas (TNFRSF6)-associated via death domain;FAS-associated death domain protein;Fas-associating death domain-containing protein;Fas-associating protein with death domain;GIG3;growth-inhibiting gene 3 protein;Mediator of receptor induced toxicity;mediator of receptor-induced toxicity;MORT1;Protein FADD
- Extra Details:
- The protein is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade.
- Shipping Conditions:
- Blue Ice