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AN302077L

Recombinant Phospho-PTP1B (Ser352) Monoclonal Antibody

Size

£252.90

Was £281.00

SKU:
AN302077L
Additional Names:
PTPN,PTPN1,PTP1B
Application:
WB
Concentration:
1 mg/ml
Purification:
Protein A Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Immunogen:
Phosphorylated human PTP1B (Ser352) peptide
Clone:
A801
Uniprot:
P18031
Synonyms:
protein tyrosine phosphatase, placental;protein-tyrosine phosphatase 1B;PTP1B;tyrosine-protein phosphatase non-receptor type 1
Extra Details:
PTP1B is a tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response and mediates dephosphorylation of EIF2AK3/PERK, inactivating the protein kinase activity of EIF2AK3/PERK. During metaphase, PTP1B is phosphorylated by protein kinase C (PKC) at S352, which is also phosphorylated in response to osmotic stress, but do not markedly change PTP1B activity.
Shipping Conditions:
Blue Ice