AN302069L
Recombinant Vitamin D Receptor Monoclonal Antibody
Size
£252.90
Was £281.00
- SKU:
- AN302069L
- Additional Names:
- NR1I,nuclear receptor subfamily,PPP1R,member,VDR,NR1I1,PPP1R163,group I,member 1,nuclear receptor subfamily 1,vitamin D receptor
- Application:
- WB, IP
- Concentration:
- 1 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Peptide. This information is proprietary to PTMab.
- Clone:
- A789
- Uniprot:
- P11473
- Synonyms:
- 1,25-dihydroxyvitamin D3 receptor;NR1I1;nuclear receptor subfamily 1 group I member 1;PPP1R163;protein phosphatase 1, regulatory subunit 163;vitamin D (1,25- dihydroxyvitamin D3) receptor;vitamin D nuclear receptor variant 1;vitamin D3 receptor;vitamin D3 receptor isoform VDRA
- Extra Details:
- This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding different proteins.
- Shipping Conditions:
- Blue Ice