AN302065L
Recombinant SMARCC2/BAF170 Monoclonal Antibody
Size
£252.90
Was £281.00
- SKU:
- AN302065L
- Additional Names:
- Rsc,BAF,CRACC,SMARCC,SMARCC2,BAF170,CRACC2,Rsc8
- Application:
- Flow Cytometry, IHC, WB, IP
- Concentration:
- 1 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Peptide. This information is proprietary to PTMab.
- Clone:
- A785
- Uniprot:
- Q8TAQ2
- Synonyms:
- BAF170;BRG1-associated factor 170;chromatin remodeling complex BAF170 subunit;CRACC2;CSS8;mammalian chromatin remodeling complex BRG1-associated factor 170;Rsc8;SWI/SNF complex 170 kDa subunit;SWI/SNF complex subunit SMARCC2;SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2;SWI3-like protein
- Extra Details:
- Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology).Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by alteringDNA-histone contacts within a nucleosome in an ATP-dependent manner. BAF170 is one of the core subunits of the SWI/SNF complex,which is necessary for efficient nucleosome remodeling by Brg1 in vitro. While BAF170 has been shown to be part of the SWI/SNF complexin non-pluripotent cells, it is absent in pluripotent embryonic stem (ES) cells. Research studies have shown that expression of BAF170 is upregulated in neurons/neuronal progenitors upon differentiation of mouse ES cells with retinoic acid, and exogenous expression of BAF170leads to loss of stem cell pluripotency and self renewal.
- Shipping Conditions:
- Blue Ice