AN302052L
Recombinant ATP Citrate Lyase Monoclonal Antibody
Size
£252.90
Was £281.00
- SKU:
- AN302052L
- Additional Names:
- OTTHUMP,ACLY,ACL,ATPCL,CLATP,ATP citrate (pro-S) lyase,ATP citrate lyase,ATP citrate synthase,ATP-citrate (pro-S-)-lyase,ATPcitrate synthase,ATP-citrate synthase,Citrate cleavage enzyme,OTTHUMP00000164773
- Application:
- IHC, WB
- Concentration:
- 1 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Peptide. This information is proprietary to PTMab.
- Clone:
- A772
- Uniprot:
- P53396
- Synonyms:
- ACL;ATP-citrate (pro-S-)-lyase;ATP-citrate synthase;ATPCL;citrate cleavage enzyme;CLATP
- Extra Details:
- ATP-citrate lyase (ACL) is a homotetramer that catalyzes the formation of acetyl-CoA and oxaloacetate (OAA) in the cytosol, which is the keystep for the biosynthesis of fatty acids, cholesterol and acetylcholine, as well as for glucogenesis. Nutrients and hormones regulate theexpression level and phosphorylation of ATP-citrate lyase. It is phosphorylated by GSK-3 on Thr446 and Ser450. Ser455 of ATP-citrate lyasehas been reported to be phosphorylated by PKA and Akt. Phosphorylation on Ser455 abolishes the homotropic allosteric regulation by citrateand enhances the catalytic activity of the enzyme.
- Shipping Conditions:
- Blue Ice