AN302032L
Recombinant PNKP Monoclonal Antibody
Size
£252.90
Was £281.00
- SKU:
- AN302032L
- Additional Names:
- AOA,EIEE,PNKP,AOA4,EIEE10,MCSZ,PNK
- Application:
- IHC, WB
- Concentration:
- 1 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Peptide. This information is proprietary to PTMab.
- Clone:
- A752
- Uniprot:
- Q96T60
- Synonyms:
- AOA4;bifunctional polynucleotide phosphatase/kinase;CMT2B2;DNA 5'-kinase/3'-phosphatase;EIEE10;Homo sapiens polynucleotide kinase 3'-phosphatase (PNKP);MCSZ;PNK;Polynucleotide kinase-3'-phosphatase
- Extra Details:
- PNK (polynucleotide kinase) is a DNA repair enzyme that participates in single strand break repair and non-homologous end rejoining (NHEJ) for double strand breaks. PNK possesses a 5'-DNA kinase activity and a 3'-DNA phosphatase activity. It has three domains, a C terminal kinase domain, a central phosphatase domain, and an N-terminal forkhead associated (FHA) domain that is responsible for protein protein interactions. Reduction in expression of PNK by RNAi sensitizes cells to ionizing radiation and topoisomerase I inhibitors.
- Shipping Conditions:
- Blue Ice