AN302024L
Recombinant Histone H3.3 Monoclonal Antibody
Size
£252.90
Was £281.00
- SKU:
- AN302024L
- Additional Names:
- H3F,histone H,H3F3A,H3.3A,H3F3,histone H3.3,family 3B (H3.3B),H3 histone,H3 histone family 3A,H3 histone family 3B,H3.3,H33,Histone H3.3Q,Histone H3.A,Histone H3.B,MGC87782,MGC87783,H3.3B,H3F3B,H3-3A,H3-3B,PP781
- Application:
- IHC, WB
- Concentration:
- 1 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Peptide. This information is proprietary to PTMab.
- Clone:
- A744
- Uniprot:
- P84243
- Synonyms:
- H3 histone family member 3A;H3 histone family member 3B;H3 histone, family 3A;H3 histone, family 3B (H3.3B);H3-3A;H3-3B;H3.3A;H3.3B;H3F3;H3F3A;H3F3B;histone H3.3
- Extra Details:
- Histone H3.3 is a histone H3 variant that replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
- Shipping Conditions:
- Blue Ice