AN302015L
Recombinant PDK4 Monoclonal Antibody
Size
£252.90
Was £281.00
- SKU:
- AN302015L
- Additional Names:
- PDK,PDHK,Pyruvate dehydrogenase lipoamide kinase isozyme,PDK4 PDHK,PDK4,FLJ40832,mitochondrial,Pyruvate dehydrogenase lipoamide kinase isozyme 4,PDK4 PDHK4,PDHK4,[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4,Pyruvate dehydrogenase [lipoamide] kinase isozyme 4 mitochondrial,Pyruvate dehydrogenase kinase 4,Pyruvate dehydrogenase kinase isoenzyme 4,Pyruvate dehydrogenase kinase isoform 4,Pyruvate dehydrogenase kinase isozyme 4,Pyruvate dehydrogenase kinase isozyme 4 mitochondrial
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Mouse, Rat
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Peptide. This information is proprietary to PTMab.
- Clone:
- A735
- Uniprot:
- Q16654
- Synonyms:
- [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial;[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial;Pyruvate dehydrogenase kinase isoform 4;pyruvate dehydrogenase kinase, isoenzyme 4;pyruvate dehydrogenase kinase, isozyme 4;pyruvate dehydrogenase, lipoamide, kinase isozyme 4, mitochondrial
- Extra Details:
- Pyruvate dehydrogenase kinase isoform4 (PDK4) is also named as PDHK4 and belongs to the PDK/BCKDK protein kinase family. It is upregulated by starvation in many tissues of the body during starvation. This causes inactivation of the pyruvate dehydrogenase complex which blocks pyruvate oxidation and conserves lactate and alanine for gluconeogenesis. Enhanced PDK4 expression may be caused by the increase in free fatty acids that occurs during starvation. Free fatty acids can activate peroxisome proliferator-activated receptor A Alpha (PPARA Alpha), and activation of PPARA Alpha can promote PDK4 expression.
- Shipping Conditions:
- Blue Ice