AN302008L
Recombinant Cadherin-6 Monoclonal Antibody
Size
£252.90
Was £281.00
- SKU:
- AN302008L
- Additional Names:
- CAD,Cadherin 6 type,CADH,CAD6,CADH6,Cadherin 6,Cadherin 6 type 2,Cadherin 6 type 2 K cadherin (fetal kidney),Cadherin fetal kidney,Cadherin6,Cadherin-6,CDH 6,KCAD,K-Cadherin,Kidney Cadherin,CDH6
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Peptide. This information is proprietary to PTMab.
- Clone:
- A728
- Uniprot:
- P55285
- Synonyms:
- CAD6;cadherin 6, type 2, K-cadherin (fetal kidney);cadherin-6;KCAD;Kidney cadherin
- Extra Details:
- Cadherin-6, also known as kidney cadherin (K-Cadherin, CDH6) is a type II classical cadherin. While it was reported to have a tumor suppressor function in cholangiocarcinoma, cadherin-6 expression was shown to be a marker of epithelial mesenchymal transition, and positively correlated with stage and metastasis of papillary thyroid carcinoma. In related studies, cadherin-6 was shown to interact with GABARAP and related proteins to restrain autophagy, thereby promoting metastatic behavior. Cadherin-6 has since been proposed as an antibody-drug conjugate target for the treatment of ovarian and renal cancers.
- Shipping Conditions:
- Blue Ice