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AN301984L

Recombinant PEDF Monoclonal Antibody

Size

£252.90

Was £281.00

SKU:
AN301984L
Additional Names:
PIG,EPC,SERPINF,Serpin F,SERPINF1,EPC-1,OI12,OI6,PEDF,PIG35,Cell Proliferation-Inducing Gene 35 Protein,Pigment Epithelium-Derived Factor,Serpin F1
Application:
WB
Concentration:
1 mg/ml
Purification:
Protein A Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Immunogen:
Peptide. This information is proprietary to PTMab.
Clone:
A704
Uniprot:
P36955
Synonyms:
alpha-2 antiplasmin;cell proliferation-inducing gene 35 protein;EPC-1;OI12;OI6;PEDF;PIG35;pigment epithelium-derived factor;serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1;Serpin F1;serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1;testis tissue sperm-binding protein Li 70n
Extra Details:
PEDF also known as serpin F1 (SERPINF1), is a multifunctional secreted protein that has anti-angiogenic, anti-tumorigenic, and neurotrophic functionsis. It is an approximately 50-kDa secreted protein that is widely expressed, including by osteoblasts and osteoclasts. PEDF is also one of the most abundant secretory products of adipocytes, and circulating concentrations of PEDF correlate positively with body fat mass and INS resistance. PEDF is a neurotrophic factor involved in neuronal differentiation in retinoblastoma cells. Mutations in this gene were found in individuals with osteogenesis imperfecta, type VI.
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