AN301980L
Recombinant COUP-TFII Monoclonal Antibody
Size
£252.90
Was £281.00
- SKU:
- AN301980L
- Additional Names:
- SVP,COT,CHTD,NF-E,COUP transcription factor,Apolipoprotein AI regulatory protein,Apolipoprotein A-I regulatory protein,Nuclear receptor subfamily 2 group F member,TFCOUP,COUP TF,COUP-TF,ARP,NR2F2,ARP1,CHTD4,COUPTFB,COUPTFII,NF-E3,SVP40,TFCOUP2,Apolipoprotein AI regulatory protein 1,Apolipoprotein A-I regulatory protein 1,ARP-1,COT2,COUP TF2,COUP transcription factor 2,COUP transcription factor II,COUP-TF II,COUP-TF2,NR2F1,Nuclear receptor subfamily 2 group F member 2
- Application:
- ChIP, IHC, WB
- Concentration:
- 1 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Peptide. This information is proprietary to PTMab.
- Clone:
- A696
- Uniprot:
- P24468
- Synonyms:
- ADP-ribosylation factor related protein 1;apolipoprotein A-I regulatory protein 1;apolipoprotein AI regulatory protein 1;ARP-1;ARP1;chicken ovalbumin upstream promoter transcription factor 2;chicken ovalbumin upstream promoter-transcription factor I;CHTD4;COUP transcription factor 2;COUP transcription factor II;COUPTF2;COUPTFB;COUPTFII;NF-E3;Nuclear receptor subfamily 2 group F member 2;SRXX5;SVP40;TFCOUP2
- Extra Details:
- Chicken ovalbumin upstream promoter transcription factor (COUP-TF) belongs to the NR2 subfamily of the nuclear hormone receptor family. COUP-TFI and COUP-TFII are two of the well-characterized members in the NR2 subfamily. These two members are highly conserved in their two zinc-finger DNA binding domains (DBD) and the ligand binding domain (LBD), and function as repressors or activators of downstream target genes to regulate different biological processes. COUP-TFI and II bind to 5'-AGGTCA-3' motif palindromes, either directly or indirectly, through heterodimer formation with other proteins (e.g. RXRs) to regulate downstream target gene expression. COUP-TFI is involved in neuronal development, tissue patterning, and differentiation. COUP-TFII has been shown to be involved in angiogenesis, glucose homeostasis, and mesenchymal cell commitment.
- Shipping Conditions:
- Blue Ice