AN301964L
Recombinant DPP4/CD26 Monoclonal Antibody
Size
£252.90
Was £281.00
- SKU:
- AN301964L
- Additional Names:
- DPP,dipeptidylpeptidase,dipeptidyl-peptidase,dipeptidyl peptidase,T-cell activation antigen CD,adenosine deaminase complexing protein,DPP4,ADABP,ADCP2,CD26,DPPIV,TP103,Dipeptidyl peptidase IV,ADCP-2,dipeptidyl-peptidase 4,dipeptidyl peptidase 4,DPP IV,dipeptidylpeptidase 4,T-cell activation antigen CD26,adenosine deaminase complexing protein 2,dipeptidylpeptidase IV,Dipeptidyl peptidase IV (DPP IV),ADABP Protein,ADCP2 Protein,CD26 Protein,DPPIV Protein,Human,TP103 Protein
- Application:
- IHC, WB
- Concentration:
- 1 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant human DPP4/CD26 fragment
- Clone:
- A680
- Uniprot:
- P27487
- Synonyms:
- ADABP;ADCP-2;ADCP2;adenosine deaminase complexing protein 2;CD26;dipeptidyl peptidase 4;dipeptidyl peptidase IV;dipeptidylpeptidase 4;dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2);DPP IV;DPPIV;Gly-Pro naphthylamidase;Post-proline dipeptidyl aminopeptidase IV;T-cell activation antigen CD26;TP103;Xaa-Pro-dipeptidylaminopeptidase
- Extra Details:
- DPP4/CD26 is a type II transmembrane glycoprotein expressed ubiquitously in most tissues and different cell types. The protein has a short cytoplasmic domain, transmembrane domain, a flexible stalk fragment and extracellular fragment. Both the catalytic peptide hydrolase domain and the beta-propeller ligand binding domain are located in the extracellular fragment. DPP4/CD26 is a multifunctional protein that exists in both a membrane bound form as well as an extracellular soluble form. As a peptidase, it removes N-terminal dipeptides sequentially from proteins with a proline or alanine as the penultimate P1 amino acid. DPP4/CD26 has been shown to cleave a wide range of substrates including GLP-1, BNP, etc. In addition to its peptidase activity, DPP4/CD26 interacts with multiple important cell surface ligands, such as adenosine deaminase, fibronectin, and IGF2 receptor to influence processes like T cell activation, cell migration and proliferation.
- Shipping Conditions:
- Blue Ice