AN301961L
Recombinant p40 Monoclonal Antibody
Size
£252.90
Was £281.00
- SKU:
- AN301961L
- Additional Names:
- RAB9P,RAB9P40,RABEPK,40 kDa Rab9 effector protein,8430412M01Rik,9530020d24rik,AV073337,bA65N13.1,C87311,DKFZp686P1077,OTTHUMP00000022126,OTTMUSP00000012898,OTTMUSP00000012899,OTTMUSP00000041318,p40,RAB9 effector p40,Rab9 effector protein with Kelch motifs,RABEK,RABEPK protein,RGD1310612,RP11 65N13.1,RP23-446N16.2
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant human p40 fragment
- Clone:
- A677
- Uniprot:
- Q7Z6M1
- Synonyms:
- 40 kDa Rab9 effector protein;bA65N13.1;p40;Rab9 effector p40;rab9 effector protein with kelch motifs;RAB9P40
- Extra Details:
- Rab9 GTPase is required for the transport of mannose 6-phosphate receptors from endosomes to the trans-Golgi network in living cells, and in an in vitro system that reconstitutes this process. P40 is an effector of Rab9 that interacts preferentially with the active form of Rab9. p40 does not interact with Rab7 or K-Ras, it also fails to bind Rab9 when it is bound to GDI. The protein is found in cytosol, yet a significant fraction (~30%) is associated with cellular membranes. P40 is a very potent transport factor in that the pure, recombinant protein can stimulate, significantly, an in vitro transport assay that measures transport of mannose 6-phosphate receptors from endosomes to the trans-Golgi network.
- Shipping Conditions:
- Blue Ice