AN301936L
Recombinant CD47 Monoclonal Antibody
Size
£252.90
Was £281.00
- SKU:
- AN301936L
- Additional Names:
- MER,Protein MER,Leukocyte surface antigen CD,Antigenic surface determinant protein OA,CD47,IAP,MER6,OA3,Integrin-associated protein,Leukocyte surface antigen CD47,Antigenic surface determinant protein OA3,Integrin-associated protein (IAP),Protein MER6,Antigen identified by monoclonal 1D8,CD 47,CD47 antigen,CD47 antigen (Rh-related antigen,CD47 glycoprotein,CD47 molecule,Integrin Associated Protein,Integrin associated signal transducer,integrin-associated signal transducer),MER 6,OA
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant human CD47 fragment
- Clone:
- A652
- Uniprot:
- Q08722
- Synonyms:
- antigen identified by monoclonal antibody 1D8;antigenic surface determinant protein OA3;CD47 antigen (Rh-related antigen, integrin-associated signal transducer);CD47 glycoprotein;IAP;integrin associated protein;Integrin-associated protein;integrin-associated signal transducer;leukocyte surface antigen CD47;MER6;OA3;Protein MER6;Rh-related antigen
- Extra Details:
- CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. CD47 plays an important role in memory formation and synaptic plasticity in the hippocampus. CD47 is a receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. CD47 interacts with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. CD47 may play a role in membrane transport and/or integrin dependent signal transduction. CD47 may prevent premature elimination of red blood cells. CD47 may be involved in membrane permeability changes induced following virus infection.
- Shipping Conditions:
- Blue Ice