AN301923L
Recombinant Rab8A Monoclonal Antibody
Size
£252.90
Was £281.00
- SKU:
- AN301923L
- Additional Names:
- RAB,RAB8A,MEL,RAB8,AA409338,Mel transforming oncogene,Mel transforming oncogene (derived from cell line NK14),Mel transforming oncogene (derived from cell line NK14) RAB8 homolog,Mel transforming oncogene (RAB8 homolog),MGC124948,Oncogene c mel,Oncogene c-mel,RAB8A member RAS oncogene family,Ras associated protein RAB8,Ras related protein Rab 8A,Ras-related protein Rab-8A
- Application:
- IHC, WB
- Concentration:
- 1 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant human Rab8A fragment
- Clone:
- A639
- Uniprot:
- P61006
- Synonyms:
- MEL;mel transforming oncogene (derived from cell line NK14);mel transforming oncogene (derived from cell line NK14)- RAB8 homolog;mel transforming oncogene (RAB8 homolog);oncogene c-mel;RAB8;ras-associated protein RAB8;ras-related protein Rab-8A
- Extra Details:
- The Rab8 GTPase is a member of the Ras superfamily that functions in protein transport and membrane restructuring. RAB8 has two isoforms, RAB8A and RAB8B, that share 40% amino acid identity in the C-terminal variable region. RAB8 activity is regulated by specific guanine nucleotide exchange factors (GEFs), that mediate GTP loading, and GTPase activating proteins (GAPs) that convert them into the inactive GDP-bound form. RAB8 participates in recycling of the A Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors to the dendritic spine surface as well as in the intracellular transport of the metabotropic glutamate receptor type 1 in neuronal cells. Rab8 is activated at the base of the cilium by its guanine nucleotide exchanger Rabin8.
- Shipping Conditions:
- Blue Ice