AN301912L
Recombinant IL-1RA Monoclonal Antibody
Size
£252.90
Was £281.00
- SKU:
- AN301912L
- Additional Names:
- IL1F,MVCD,IL1RN,DIRA,ICIL-1RA,IL-1RN,IL-1ra,IL-1ra3,IL1F3,IL1RA,IRAP,MVCD4,Anakinra,IL1 inhibitor,Interleukin-1 receptor antagonist protein,F630041P17Rik,ICIL 1RA,ICIL1RA,IL1RN (IL1F3),Interleukin 1 receptor antagonist,Intracellular IL 1 receptor antagonist type II,Intracellular interleukin 1 receptor antagonist (icIL 1ra),MGC10430,Type II interleukin 1 receptor antagonist
- Application:
- IHC, WB, IF
- Concentration:
- 1 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant human IL-1RA fragment
- Clone:
- A628
- Uniprot:
- P18510
- Synonyms:
- DIRA;ICIL-1RA;IL-1ra;IL-1ra3;IL-1RN;IL1 inhibitor;IL1F3;IL1RA;interleukin-1 receptor antagonist protein;intracellular IL-1 receptor antagonist type II;intracellular interleukin-1 receptor antagonist (icIL-1ra);IRAP;MVCD4;type II interleukin-1 receptor antagonist
- Extra Details:
- The founding members of the interleukin-1 (IL-1) superfamily include pro-inflammatory cytokines IL-1A Alpha, IL-1B Beta and IL-1 receptor antagonist (IL-1RA). At least six similar proteins have been recently identified, including a homolog of IL-1RA (IL1F5). IL-1a, IL-1b and IL-1RA are mainly expressed in macrophages, monocytes, and dendritic cells. IL-1RA acts as an anti-inflammatory cytokine, binding the IL-1 receptor to limit the response to inflammation. Because it plays a key role in regulating the inflammatory response, recombinant IL-1RA is a therapeutic agent used in the treatment of diseases such as rheumatoid arthritis. Alternatively, mutation of the corresponding IL-1RA gene may be associated with susceptibility to the development of specific cancers.
- Shipping Conditions:
- Blue Ice