AN301889L
Recombinant KIF5B Monoclonal Antibody
Size
£252.90
Was £281.00
- SKU:
- AN301889L
- Additional Names:
- HEL-S,KIF5B,HEL-S-61,KINH,KNS,KNS1,UKHC
- Application:
- IHC, WB
- Concentration:
- 1 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant human KIF5B fragment
- Clone:
- A605
- Uniprot:
- P33176
- Synonyms:
- conventional kinesin heavy chain;epididymis secretory protein Li 61;HEL-S-61;kinesin 1 (110-120kD);kinesin heavy chain;kinesin-1 heavy chain;KINH;KNS;KNS1;ubiquitous kinesin heavy chain;UKHC
- Extra Details:
- KIF5B is a member of kinesin superfamily protein 5 (KIF5). KIF5 consists of three family members referred to as KIF5A, KIF5B, and KIF5C. KIF5A and KIF5C are specifically expressed in neurons whereas KIF5B is expressed ubiquitously. Targeted disruption of the kif5B gene resulted in embryonic lethality. These and other studies demonstrate that KIF5B plays an important role in the localization and distribution of major organelles, including the mitochondria and lysosome, and can contribute to autophagy. In addition, gene rearrangements involving KIF5B fusions to ALK and RET have been identified as drivers for lung cancer and other malignancies.
- Shipping Conditions:
- Blue Ice