AN301874L
Recombinant Caspase-7 Monoclonal Antibody
Size
£252.90
Was £281.00
- SKU:
- AN301874L
- Additional Names:
- Mch,Lice,CASP,Lice2,Mch3,Casp7,CASP-7,Caspase 7,CMH-1,ICE-LAP3
- Application:
- IHC, WB
- Concentration:
- 1 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Mouse, Rat
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant human Caspase-7 fragment
- Clone:
- A586
- Uniprot:
- P97864
- Synonyms:
- AI314680;apoptotic protease Mch-3;casp;CASP-7;caspase-7;CMH-1;cysteine protease LICE2;ICE-;ICE-IAP3;mCASP-7;Mch3
- Extra Details:
- Caspase-7, also named as CMH-1, Mch3 and ICE-LAP3, has been identified as a major contributor to the execution of apoptosis. Caspase-7, like caspase-3, is an effector caspase that is responsible for cleaving downstream substrates such as ADP-ribose polymerase and PARP. During apoptosis, caspase-7 is activated through proteolytic processing by upstream caspases at Asp23, Asp198, and Asp206 to produce the mature subunits. Similar to caspase-2 and -3, caspase-7 preferentially cleaves substrates following the recognition sequence DEVD.
- Shipping Conditions:
- Blue Ice