AN301865L
Recombinant Glypican-3 Monoclonal Antibody
Size
£252.90
Was £281.00
- SKU:
- AN301865L
- Additional Names:
- MXR,GPC,UNQ,PRO,CDw,ADAM,Protein FOAP,Secreted glypican,Glypican proteoglycan,Sialic acid-binding Ig-like lectin,C20orf,OCI,GPC3,DGSX,GTR2-2,MXR7,OCI-5,SDYS,SGB,SGBS,SGBS1,glypican-3,CDw329,Glypican 3,Glypican proteoglycan 3,Glypican-3 [Precursor],GTR2 2,Heparan sulphate proteoglycan,Intestinal protein OCI 5,Intestinal protein OCI-5,OCI 5,Protein FOAP-9,Secreted glypican-3,Sialic acid-binding Ig-like lectin 9,SIGLEC9,Siglec-9,ADAM33,C20orf153,UNQ873,PRO1891,OCI5
- Application:
- IHC, WB, IF
- Concentration:
- 1 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant human Glypican-3 fragment
- Clone:
- A577
- Uniprot:
- P51654
- Synonyms:
- DGSX;glypican proteoglycan 3;glypican-3;GTR2-2;heparan sulphate proteoglycan;intestinal protein OCI-5;MXR7;OCI-5;SDYS;secreted glypican-3;SGB;SGBS;SGBS1
- Extra Details:
- Glypican 3 belongs to Glypicans (GPCs), a family of glycosylphosphatidylinositol (GPI)-anchored heparan sulphate proteoglycans (HSPGs) that may play a role in the control of cell division and growth regulation. In mammals, there are six GPCs (GPC1 to GPC6), all of which have a similar core-protein size of approx. 60 kDa and the clustering of glycosaminoglycan attachment site near the C-terminus. They are tethered to the cell surface by GPI linkages, which can be cleaved by endogenous phospholipases, thus releasing the protein. Glypican 3 (GPC3) is highly expressed in many tissues during development and plays an important role in the regulation of embryonic growth. Loss-of-function mutations of GPC3 result in the Simpson-Golabi-Behmel overgrowth syndrome (SGBS), and Gpc-3 null mice display developmental overgrowth. In hepatocellular carcinoma (HCC), the overexpression of glypican 3 has been demonstrated to be a reliable diagnostic indicator.
- Shipping Conditions:
- Blue Ice