AN301864L
Recombinant CX3CR1 Monoclonal Antibody
Size
£252.90
Was £281.00
- SKU:
- AN301864L
- Additional Names:
- GPR,CCRL,GPRV,CX3CR,CMKDR,CMKBRL,CX3CR1,CCRL1,CMKBRL1,CMKDR1,GPR13,GPRV28,V28,Beta chemokine receptor-like 1,CMK-BRL1,CMK-BRL-1,CX3C chemokine receptor 1,C-X3-C CKR-1,C-X3-C motif chemokine receptor 1,fractalkine receptor,G-protein coupled receptor 13
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant human CX3CR1 fragment
- Clone:
- A576
- Uniprot:
- P49238
- Synonyms:
- beta chemokine receptor-like 1;C-X3-C CKR-1;CCRL1;chemokine (C-C) receptor-like 1;chemokine (C-X3-C motif) receptor 1;chemokine (C-X3-C) receptor 1;CMK-BRL-1;CMK-BRL1;CMKBRL1;CMKDR1;CX3C chemokine receptor 1;fractalkine receptor;G-protein coupled receptor 13;GPR13;GPRV28;V28
- Extra Details:
- CX3CR1 is a G-protein-coupled seven-transmembrane chemokine receptor, also known as GPR13 or V28. It is expressed on microglia, astrocytes, NK cells, monocytes/macrophages, and a subpopulation of T cells. CX3CR1 is the receptor for fractalkine (CX3CL1) and mediates both its adhesive and migratory functions. It also acts as coreceptor with CD4 for HIV-1 virus envelope protein (in vitro), and some variations in the gene of CX3CR1 lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Defects in CX3CR1 are a cause of susceptibility to age-related macular degeneration type 12 (ARMD12).
- Shipping Conditions:
- Blue Ice