AN301844L
Recombinant VAV3 Monoclonal Antibody
Size
£252.90
Was £281.00
- SKU:
- AN301844L
- Additional Names:
- VAV,VAV3
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant human VAV3 fragment
- Clone:
- A556
- Uniprot:
- Q9UKW4
- Synonyms:
- guanine nucleotide exchange factor VAV3;vav 3 guanine nucleotide exchange factor;vav 3 oncogene;VAV-3
- Extra Details:
- Vav proteins belong to the Dbl family of guanine nucleotide exchange factors (GEFs) for Rho/Rac small GTPases. The three identified mammalian VAV proteins (VAV1, VAV2 and VAV3) differ in their expression. Vav1 is expressed only in hematopoietic cells and is involved in the formation of the immune synapse. VAV2 and VAV3 are more ubiquitously expressed. VAV proteins contain the Dbl homology domain, which confers GEF activity, as well as protein interaction domains that allow them to function in pathways regulating actin cytoskeleton organization.
- Shipping Conditions:
- Blue Ice