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AN301825L

Recombinant LMO4 Monoclonal Antibody

Size

£252.90

Was £281.00

SKU:
AN301825L
Additional Names:
LMO,LMO4
Application:
WB
Concentration:
1 mg/ml
Purification:
Protein A Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Immunogen:
Recombinant human LMO4 fragment
Clone:
A537
Uniprot:
P61968
Synonyms:
breast tumor autoantigen;LIM domain only protein 4;LIM domain transcription factor LMO4;LIM-only 4 protein;LMO-4
Extra Details:
LMO4 is a LIM zinc-binding domain-containing protein. LMO4 cDNA was first isolated from a breast tumor cDNA library. This transcriptional modulator is overexpressed in several epithelial cancers such as prostate, pancreas, and breast. LMO4 exhibits pro-oncogenic activities by inducing centrosome amplification and mitotic spindle abnormalities. LMO4 is also expressed in the brain, in regions involved in learning and the regulation of motivated behavior. In the basolateral amygdala, LMO4 functions to negatively regulate fear learning. Furthermore, in the nucleus accumbens, LMO4 was found to regulate the behavioral effects of cocaine.
Shipping Conditions:
Blue Ice