AN301790L
Recombinant PTPN12 Monoclonal Antibody
Size
£252.90
Was £281.00
- SKU:
- AN301790L
- Additional Names:
- PTPG,PTPN,PTPG1,PTP-PEST,PTPN12,PTP-PEST,Protein tyrosine phosphatase G1,Protein tyrosine phosphatase non receptor type 12,Protein-tyrosine phosphatase G1,PTN12,PTP PEST,Tyrosine protein phosphatase non receptor type 12,Tyrosine-protein phosphatase non-receptor type 12
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant human PTPN12 fragment
- Clone:
- A502
- Uniprot:
- Q05209
- Synonyms:
- protein-tyrosine phosphatase G1;PTP-PEST;PTPG1;tyrosine-protein phosphatase non-receptor type 12
- Extra Details:
- PTPN12 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains a C-terminal PEST motif, which serves as a protein-protein interaction domain, and may regulate protein intracellular half-life. This PTP was found to bind and dephosphorylate the product of the oncogene c-ABL and thus may play a role in oncogenesis. This PTP was also shown to interact with, and dephosphorylate, various products related to cytoskeletal structure and cell adhesion, such as p130 (Cas), CAKbeta/PTK2B, PSTPIP1, and paxillin. This suggests it has a regulatory role in controlling cell shape and mobility.
- Shipping Conditions:
- Blue Ice