AN301785L
Recombinant ALIX Monoclonal Antibody
Size
£252.90
Was £281.00
- SKU:
- AN301785L
- Additional Names:
- AIP,DRIP,KIAA,PDCD6IP,AIP1,ALIX,DRIP4,HP95,KIAA1375
- Application:
- IHC, WB, IP
- Concentration:
- 1 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant human ALIX fragment
- Clone:
- A493
- Uniprot:
- Q8WUM4
- Synonyms:
- AIP1;ALG-2 interacting protein 1;ALG-2-interacting protein 1;ALG-2-interacting protein X;ALIX;apoptosis-linked gene 2-interacting protein X;dopamine receptor interacting protein 4;DRIP4;HP95;PDCD6-interacting protein;programmed cell death 6-interacting protein
- Extra Details:
- Programmed cell death 6-interacting protein (PDCD6IP), plays an important role in the endosomal sorting complexes required for transport (ESCRT) pathway in the abscission stage of cytokinesis and apoptosis. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the protein binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. It also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this protein and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death.
- Shipping Conditions:
- Blue Ice