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AN301760L

Recombinant CD7 Monoclonal Antibody

Size

£252.90

Was £281.00

SKU:
AN301760L
Additional Names:
T cell antigen CD,T cell surface antigen Leu,LEU,CD7,GP40,LEU-9,TP41,Tp40,CD7 antigen,CD7 antigen (p41),CD7 molecule,CD7_HUMAN,LEU 9,LEU9,p41 protein,T cell antigen CD7,T cell leukemia antigen,T cell surface antigen Leu 9,T-cell antigen CD7,T-cell leukemia antigen,T-cell surface antigen Leu-9,Tp 40,CD7,CD7 antigen (p41),CD7 antigen,CD7 molecule,CD7_HUMAN,GP40,LEU 9,LEU9,p41 protein,T cell antigen CD7,T cell leukemia antigen,T cell surface antigen Leu 9,T-cell antigen CD7,T-cell leukemia
Application:
Flow Cytometry, IHC, WB, IF
Concentration:
1 mg/ml
Purification:
Protein A Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Immunogen:
Recombinant human CD7 fragment
Clone:
A468
Uniprot:
P09564
Synonyms:
CD7 antigen (p41);GP40;LEU-9;p41 protein;T-cell antigen CD7;T-cell leukemia antigen;T-cell surface antigen Leu-9;Tp40;TP41
Extra Details:
The CD7 antigen is a membrane-embedded glycoprotein with a molecular weight of 37-40 kDa and a member of the immunoglobulin supergene family. It plays an important role in T-cell and T-cell/B-cell interactions during early lymphoid development. CD7 is the earliest T-cell-associated molecule to appear in stem cells and prethymic stages and extends its expression all the way to the mature T cells. This molecule is also present on NK cells. In addition, the pluripotent bone marrow stem cells may express CD7. A subpopulation of AML, particularly those with monocytic or megakaryocytic differentiation, may express CD7. Lack of CD7 expression can be used for the detection of T-cell lymphoproliferative disorders, such as mycosis fungoides/Sezary syndrome and adult T-cell leukemia/lymphoma. However, normal and reactive T cells often demonstrate variable degree of CD7 loss.
Shipping Conditions:
Blue Ice