AN301758L
Recombinant ILF3 Monoclonal Antibody
Size
£252.90
Was £281.00
- SKU:
- AN301758L
- Additional Names:
- ILF,MMP,Mpp,DRBP,NF-AT,MPHOSPH,TCP,ILF3,CBTF,DRBF,DRBP76,MMP4,MPHOSPH4,MPP4,NF-AT-90,NF110,NF110b,NF90,NF90a,NF90b,NFAR,NFAR-1,NFAR2,TCP110,TCP80,Double stranded RNA binding protein 76,Double-stranded RNA-binding protein 76,Interleukin enhancer binding factor 3,Interleukin enhancer-binding factor 3,M phase phosphoprotein 4,M-phase phosphoprotein 4,NF AT 90,Nuclear factor associated with dsRNA,Nuclear factor of activated T cells 90 kDa,Nuclear factor of activated T-cells 90 kDa,Translational
- Application:
- Flow Cytometry, IHC, WB, IF
- Concentration:
- 1 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant human ILF3 fragment
- Clone:
- A466
- Uniprot:
- Q12906
- Synonyms:
- CBTF;Double-stranded RNA-binding protein 76;double-stranded RNA-binding protein, 76 kD;DRBF;DRBP76;dsRNA binding protein NFAR-2/MPP4;interleukin enhancer binding factor 3, 90kD;interleukin enhancer binding factor 3, 90kDa;interleukin enhancer-binding factor 3;M phase phosphoprotein 4, nuclear factor associated with DS RNA;M-phase phosphoprotein 4;MMP4;MPHOSPH4;MPP4;MPP4110;NF-AT-90;NF110;NF110b;NF90;NF90a;NF90b;NF90c;NF90ctv;NFAR;NFAR-1;NFAR-2;NFAR110;NFAR2;NFAR90;nuclear factor associated with dsRNA;nuclear factor of activated T-cells 110 kDa;nuclear factor of activated T-cells 90 kDa;nuclear factor of activated T-cells, 90 kD;TCP110;TCP80;translational control protein 80
- Extra Details:
- Interleukin enhancer-binding factor 3 (ILF3) is a double-stranded RNA (dsRNA) binding protein that complexes with other proteins, dsRNAs, small noncoding RNAs, and mRNAs to regulate gene expression and stabilize mRNAs. This protein (NF90, ILF3) forms a heterodimer with a 45 kDa transcription factor (NF45, ILF2) required for T-cell expression of interleukin 2. This complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. In contrast, an isoform (NF110) of this gene that is predominantly restricted to the nucleus has only minor effects on cell growth when its levels are reduced. Alternative splicing results in multiple transcript variants encoding distinct isoforms. ILF3 exists main two isoforms NFAR-1 (90 kDa) and -2 (110 kDa). Upon viral infection, ILF3 accumulates in the cytoplasm and participates in the innate antiviral response.
- Shipping Conditions:
- Blue Ice