AN301725L
Recombinant PDK2 Monoclonal Antibody
Size
£252.90
Was £281.00
- SKU:
- AN301725L
- Additional Names:
- PDK,PDHK,Pyruvate dehydrogenase kinase isoform,Pyruvate dehydrogenase lipoamide kinase isozyme,[Pyruvate dehydrogenase [lipoamide]] kinase isozyme,isozyme,PDK2,PDHK2,PDKII,[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2,isozyme 2,mitochondrial,Pyruvate dehydrogenase kinase,Pyruvate dehydrogenase kinase isoform 2,Pyruvate dehydrogenase lipoamide kinase isozyme 2
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant human PDK2 fragment
- Clone:
- A433
- Uniprot:
- Q15119
- Synonyms:
- [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial;PDH kinase 2;PDHK2;PDKII;Pyruvate dehydrogenase kinase isoform 2;pyruvate dehydrogenase kinase, isoenzyme 2;pyruvate dehydrogenase kinase, isozyme 2;pyruvate dehydrogenase, lipoamide, kinase isozyme 2, mitochondrial
- Extra Details:
- [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2 (PDK2) is a kinase that plays a key role in the regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. This inhibits pyruvate dehydrogenase activity, and thereby regulates metabolite flux through the tricarboxylic acid cycle, down-regulates aerobic respiration and inhibits the formation of acetyl-coenzyme A from pyruvate. PDK2 Mediates cellular responses to insulin and plays an important role in maintaining normal blood glucose levels and in metabolic adaptation to nutrient availability.
- Shipping Conditions:
- Blue Ice