AN301704L
Recombinant HIP2/LIG Monoclonal Antibody
Size
£252.90
Was £281.00
- SKU:
- AN301704L
- Additional Names:
- HIP,UBC,UBE2K,E2-25K,HIP2,HYPG,LIG,UBC1,HIP-2,Huntingtin-Interacting Protein 2,Ubiquitin Carrier Protein,Ubiquitin-Conjugating Enzyme E2 K,Ubiquitin-Conjugating Enzyme E2(25K),Ubiquitin-Conjugating Enzyme E2-25 kDa,Ubiquitin-Conjugating Enzyme E2-25K,Ubiquitin-Protein Ligase
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant human HIP2/LIG fragment
- Clone:
- A412
- Uniprot:
- P61086
- Synonyms:
- E2 ubiquitin-conjugating enzyme K;E2-25K;E2(25K);HIP-2;HIP2;huntingtin-interacting protein 2;HYPG;LIG;UBC1;ubiquitin carrier protein;ubiquitin conjugating enzyme E2K;ubiquitin-conjugating enzyme E2 K;ubiquitin-conjugating enzyme E2-25 KDA;ubiquitin-conjugating enzyme E2(25K);ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast);ubiquitin-protein ligase
- Extra Details:
- Huntingtin-interacting protein 2 (HIP2/LIG), is a E2 ubiquitin-conjugating enzyme, which accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro, HIP2/LIG catalyzes the synthesis of 'Lys-48'-linked polyubiquitin chains in the presence or in the absence of BRCA1-BARD1 E3 ubiquitin-protein ligase complex, while it does not transfer ubiquitin directly to but elongates monoubiquitinated substrate protein. Moreover, HIP2/LIG mediates the selective degradation of short-lived and abnormal proteins, such as the endoplasmic reticulum-associated degradation (ERAD) of misfolded lumenal proteins.
- Shipping Conditions:
- Blue Ice