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AN301683L

Recombinant RMP/C19orf2 Monoclonal Antibody

Size

£252.90

Was £281.00

SKU:
AN301683L
Additional Names:
NNX,PPP1R,C19orf,C19orf2,NNX3,PPP1R19,RMP,URI,URI1,prefoldin-like chaperone,Chromosome 19 open reading frame 2,NNX3,NNX3 protein,Protein NNX3,Protein phosphatase 1 regulatory subunit 19,RMP,RNA polymerase II subunit 5 mediating protein,RNA polymerase II subunit 5-mediating protein,RPB5 mediating protein,RPB5-mediating protein,Unconventional prefoldin RPB5 interactor,Unconventional prefoldin RPB5 interactor 1
Application:
IHC, WB, IF
Concentration:
1 mg/ml
Purification:
Protein A Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Immunogen:
Recombinant human RMP/C19orf2 fragment
Clone:
A386
Uniprot:
O94763
Synonyms:
C19orf2;NNX3;PPP1R19;Protein NNX3;Protein phosphatase 1 regulatory subunit 19;protein phosphatase 1, regulatory subunit 19;RMP;RNA polymerase II subunit 5-mediating protein;RPB5-mediating protein;unconventional prefoldin RPB5 interactor 1;URI
Extra Details:
Involved in gene transcription regulation. Acts as a transcriptional repressor in concert with the corepressor UXT to regulate androgen receptor (AR) transcription. May act as a tumor suppressor to repress AR-mediated gene transcription and to inhibit anchorage-independent growth in prostate cancer cells. Required for cell survival in ovarian cancer cells. Together with UXT, associates with chromatin to the NKX3-1 promoter region. Antagonizes transcriptional modulation via hepatitis B virus X protein.
Shipping Conditions:
Blue Ice