AN301657L
Recombinant SIGIRR Monoclonal Antibody
Size
£252.90
Was £281.00
- SKU:
- AN301657L
- Additional Names:
- Tir,Tir8,Sigirr
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Mouse
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant human SIGIRR fragment
- Clone:
- A360
- Uniprot:
- Q9JLZ8
- Synonyms:
- AI256711;S;single Ig IL-1 receptor related protein;single Ig IL-1-related receptor;single Ig IL-1R-related molecule;single Ig IL-1R-related protein;single immunoglobulin domain-containing IL1R-related protein;Ti;TIR8;toll/interleukin-1 receptor 8
- Extra Details:
- Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP.
- Shipping Conditions:
- Blue Ice