AN301640L
Recombinant ATG4B Monoclonal Antibody
Size
£252.90
Was £281.00
- SKU:
- AN301640L
- Additional Names:
- AUTL,KIAA,ATG4B,APG4B,AUTL1,cysteine protease ATG4B,KIAA0943,APG4B,AUTL1,cysteine protease ATG4B,APG4 autophagy 4 homolog B,ATG4 autophagy related 4 homolog B (S. cerevisiae),AUT like 1 cysteine endopeptidase,AUT-like 1 cysteine endopeptidase,Autophagin 1,Autophagin-1,Autophagy related 4B cysteine peptidase,Autophagy related cysteine endopeptidase 1,Autophagy related protein 4 homolog B,Autophagy-related cysteine endopeptidase 1,Autophagy-related protein 4 homolog B,hAPG4B,MGC1353
- Application:
- WB, IF
- Concentration:
- 1 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant human ATG4B fragment
- Clone:
- A343
- Uniprot:
- Q9Y4P1
- Synonyms:
- APG4 autophagy 4 homolog B;APG4B;ATG4 autophagy related 4 homolog B;AUT-like 1 cysteine endopeptidase;AUTL1;autophagin-1;autophagy-related cysteine endopeptidase 1;autophagy-related protein 4 homolog B;cysteine protease ATG4B;hAPG4B
- Extra Details:
- Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.
- Shipping Conditions:
- Blue Ice