AN301620L
Recombinant PAX8 Monoclonal Antibody
Size
£252.90
Was £281.00
- SKU:
- AN301620L
- Additional Names:
- Paired box,Paired box gene,Paired domain gene,paired box homeotic gene,PAX,PAX8,OTTHUMP00000158659,OTTHUMP00000158660,OTTHUMP00000203723,OTTHUMP00000203724,Paired box 8,Paired box gene 8,paired box homeotic gene 8,Paired box protein Pax 8,Paired box protein Pax-8,Paired domain gene 8,PAX 8
- Application:
- IHC, IF
- Concentration:
- 1 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant human PAX8 fragment
- Clone:
- A323
- Uniprot:
- Q06710
- Synonyms:
- paired box protein Pax-8;paired domain gene 8
- Extra Details:
- PAX8 is one of nine transcription factors within the PAX gene family. It has been observed to be expressed during embryonic development however expression attenuates after development in all but a few tissues. Research has indicated that over-expression of PAX proteins in general are not an initiating event in tumorgenesis however they may facilitate malignant development. PAX8 is expressed in 80-96% of all High-grade serous carcinomas (HGSC) and is commonly used as a marker for the disease. In addition PAX8 has become a useful biomarker for differentiating between mullerian mucinous and non-mullerian tumors. PAX8 has also been associated with neoplasms in the kidney and thyroid.
- Shipping Conditions:
- Blue Ice