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AN301616L

Recombinant ARPC5/p16 ARC Monoclonal Antibody

Size

£252.90

Was £281.00

SKU:
AN301616L
Additional Names:
ARC,ARPC,dJ127C,ARPC5,ARC16,dJ127C7.3,p16-Arc
Application:
Flow Cytometry, IHC, WB, IF
Concentration:
1 mg/ml
Purification:
Protein A Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Immunogen:
Recombinant human ARPC5/p16 ARC fragment
Clone:
A319
Uniprot:
O15511
Synonyms:
actin related protein 2/3 complex, subunit 5, 16kDa;actin-related protein 2/3 complex subunit 5;ARC16;arp2/3 complex 16 kDa subunit;Arp2/3 protein complex subunit p16;dJ127C7.3;p16-Arc
Extra Details:
Component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA. The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs).
Shipping Conditions:
Blue Ice