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AN301598L

Recombinant MCM5 Monoclonal Antibody

Size

£252.90

Was £281.00

SKU:
AN301598L
Additional Names:
MGC,Cell division cycle,DNA replication licensing factor MCM,Minichromosome maintenance complex component,P1-CDC,P1 CDC,CDC,MCM,MCM5,CDC46,P1-CDC46,CDC 46,CDC46 homolog,Cell division cycle 46,DNA replication licensing factor,DNA replication licensing factor MCM5,MCM 5,MGC5315,Minichromosome maintenance complex component 5,P1 CDC46,DNA replication licensing factor MCM 5,Minichromosome maintenance complex component 5,Minichromosome maintenance deficient (S. cerevisiae) 5,Minichromosome
Application:
IHC, WB, IF
Concentration:
1 mg/ml
Purification:
Protein A Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Immunogen:
Recombinant human MCM5 fragment
Clone:
A301
Uniprot:
P33992
Synonyms:
CDC46;CDC46 homolog;DNA replication licensing factor MCM5;MCM5 minichromosome maintenance deficient 5, cell division cycle 46;MGORS8;minichromosome maintenance deficient 5 (cell division cycle 46);P1-CDC46
Extra Details:
Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Interacts with MCMBP.
Shipping Conditions:
Blue Ice