AN301592L
Recombinant LysRS Monoclonal Antibody
Size
£252.90
Was £281.00
- SKU:
- AN301592L
- Additional Names:
- DFNB,KIAA,KARS,CMTRIB,DFNB89,KARS1,KARS2,KRS,EC 6.1.1.6,KARS 1,KARS 2,Lysine tRNA ligase,Lysine--tRNA ligase,LysRS,Lysyl-tRNA synthetase,SYK,KIAA0070
- Application:
- IHC, WB, IF, IP
- Concentration:
- 1 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant human LysRS fragment
- Clone:
- A291
- Uniprot:
- Q15046
- Synonyms:
- CMTRIB;DEAPLE;DFNB89;KARS;KARS2;KRS;LEPID;lysine tRNA ligase;lysine--tRNA ligase;lysRS;Lysyl-tRNA synthetase
- Extra Details:
- Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. When secreted, acts as a signaling molecule that induces immune response through the activation of monocyte/macrophages. Catalyzes the synthesis of the signaling molecule diadenosine tetraphosphate (Ap4A), and thereby mediates disruption of the complex between HINT1 and MITF and the concomitant activation of MITF transcriptional activity. Interacts with HIV-1 virus GAG protein, facilitating the selective packaging of tRNA3(Lys), the primer for reverse transcription initiation.
- Shipping Conditions:
- Blue Ice