AN301562L
Recombinant IKAROS Monoclonal Antibody
Size
£252.90
Was £281.00
- SKU:
- AN301562L
- Additional Names:
- PRO,IKZF,CVID,PPP1R,ZNFN1A,LYF,IKZF1,CVID13,Hs.54452,IK1,IKAROS,LYF1,LyF-1,PPP1R92,PRO0758,ZNFN1A1
- Application:
- IHC, WB
- Concentration:
- 1 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant human IKAROS fragment
- Clone:
- A261
- Uniprot:
- Q13422
- Synonyms:
- CLL-associated antigen KW-6;CVID13;DNA-binding protein Ikaros;Hs.54452;IK1;IKAROS;ikaros family zinc finger protein 1;LyF-1;LYF1;lymphoid transcription factor LyF-1;PPP1R92;PRO0758;protein phosphatase 1, regulatory subunit 92;zinc finger protein, subfamily 1A, 1 (Ikaros);ZNFN1A1
- Extra Details:
- Transcription regulator of hematopoietic cell differentiation. Binds gamma-satellite DNA. Plays a role in the development of lymphocytes, B- and T-cells. Binds and activates the enhancer (delta-A element) of the CD3-delta gene. Repressor of the TDT (fikzfterminal deoxynucleotidyltransferase) gene during thymocyte differentiation. Regulates transcription through association with both HDAC-dependent and HDAC-independent complexes. Targets the 2 chromatin-remodeling complexes, NuRD and BAF (SWI/SNF), in a single complex (PYR complex), to the beta-globin locus in adult erythrocytes. Increases normal apoptosis in adult erythroid cells. Confers early temporal competence to retinal progenitor cells (RPCs) (By similarity).
- Shipping Conditions:
- Blue Ice