AN301551L
Recombinant HLA-DPB1 Monoclonal Antibody
Size
£252.90
Was £281.00
- SKU:
- AN301551L
- Additional Names:
- DPB,DP beta,DPB1,HLA-DP,HLA-DP1B,HLA-DPB,HLA-DPB1,major histocompatibility complex,class II,DP beta 1,beta-1 subunit,class I,D6S221E,DMA,DMB,DP beta 1 chain,DP(W4) beta chain,DPB 1,DRB,H2Ea,HLA class II histocompatibility antigen,HLA class II histocompatibility antigen DM beta chain,HLA DMB,HLA DP1A,HLA DPB1,HLA SB alpha chain,HLA-A,HLA-A histocompatibility type,HLADM,HLA-DP histocompatibility type,HLADP1B,HLASB,HLASB histocompatibility type,Human MHC class II HLA SB alpha,LA class II
- Application:
- IHC, WB, IF, IP
- Concentration:
- 1 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant human HLA-DPB1 fragment
- Clone:
- A250
- Uniprot:
- P04440
- Synonyms:
- DPB1;HLA class II histocompatibility antigen, DP beta 1 chain;HLA class II histocompatibility antigen, DP(W4) beta chain;HLA-DP;HLA-DP histocompatibility type, beta-1 subunit;HLA-DP1B;HLA-DPB;MHC class II antigen DPB1;MHC class II HLA-DP-beta-1;MHC HLA DPB1
- Extra Details:
- Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class II molecules are generated mostly by degradation of proteins that access the endocytic route, where they are processed by lysosomal proteases and other hydrolases. Exogenous antigens that have been endocytosed by the APC are thus readily available for presentation via MHC II molecules, and for this reason this antigen presentation pathway is usually referred to as exogenous.
- Shipping Conditions:
- Blue Ice