AN301550L
Recombinant HLA-DPA1 Monoclonal Antibody
Size
£252.90
Was £281.00
- SKU:
- AN301550L
- Additional Names:
- PLT,HLA-DPA,HLA-DPA1,DP(W3),DP(W4),HLA-DP1A,HLADP,HLASB,PLT1,class II,HLA class II histocompatibility antigen DP alpha 1 chain,HLA class II histocompatibility antigen DP alpha chain,HLA DP1A,HLA DPA 1,HLA SB alpha chain,HLADPA1,HLASB histocompatibility type,Human MHC class II HLA SB alpha gene,Major histocompatibility complex class II DP alpha 1,MHC class II antigen,MHC class II DP3 alpha,MHC class II DPA1,MHC class II HLA DPA1 antigen,Primed lymphocyte test 1
- Application:
- IHC, WB, IF
- Concentration:
- 1 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
- Immunogen:
- Recombinant human HLA-DPA1 fragment
- Clone:
- A249
- Uniprot:
- P20036
- Synonyms:
- DP(W3);DP(W4);DPA1;HLA class II histocompatibility antigen, DP alpha 1 chain;HLA DPA1;HLA-DP1A;HLA-DPA;HLA-DPA1*01:03:01:New;HLA-DPA1*02:01:01:NEW;HLA-DPB1;HLA-SB alpha chain;HLADP;HLASB;MHC class II antigen DP alpha chain;MHC class II DP alpha chain;MHC class II DP3-alpha;MHC class II DPA1;MHC class II HLA-DPA1 antigen;MHC class II protein;PLT1
- Extra Details:
- Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class II molecules are generated mostly by degradation of proteins that access the endocytic route, where they are processed by lysosomal proteases and other hydrolases. Exogenous antigens that have been endocytosed by the APC are thus readily available for presentation via MHC II molecules, and for this reason this antigen presentation pathway is usually referred to as exogenous.
- Shipping Conditions:
- Blue Ice